STEAP Family Member 3, Metalloreductase (STEAP3) Peptid
STEAP3
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN984549
Kurzübersicht für STEAP Family Member 3, Metalloreductase (STEAP3) Peptid (ABIN984549)
Target
STEAP3
(STEAP Family Member 3, Metalloreductase (STEAP3))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-STEAP3 antibody (Catalog #: ARP43515_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))
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Hintergrund
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AS an endosomal ferrireductase, STEAP3 is required for efficient transferrin-dependent iron uptake in erythroid cells. It participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+) and can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. STEAP3 uses NAD(+) as acceptor (By similarity). It may play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. STEAP3 is indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCT.
Alias Symbols: STMP3, TSAP6, dudlin-2
Protein Interaction Partner: BNIP3L,PKMYT1,TPT1,BNIP3L,PKMYT1
Protein Size: 498 -
Molekulargewicht
- 56 kDa
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Gen-ID
- 55240
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NCBI Accession
- NM_182915, NP_878919
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UniProt
- A8K6E3
Target
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